Publications 2003
  1. Morré SA, Murillo LS, Bruggeman CA, Peña AS
    The Role That the Functional Asp299Gly Polymorphism in the Toll-Like Receptor-4 Gene Plays in the Susceptibility to Chlamydia trachomatis Associated Tubal Infertility.
    Infect Dis 2003 (letter);Jan 15;187:341-343.
  2. van der Paardt M, Crusius JBA, de Koning MHMT, Murillo LS, van de Stadt RJ, Dijkmans BAC, Peña AS, van der Horst-Bruinsma IE.
    CARD15
    gene mutations are not associated with ankylosing spondylitis.

    Genes and Immunity 2003;4:77-78.
  3. Xia B, Crusius JBA, Wu J, Zwiers A, van Bodegraven AA, Peña AS.

    Signal transducer and activator of transcription 6 gene G2964A polymorphism and inflammatory bowel disease.

    Clin Exp Immunol 2003;131:446-450

  4. Van Winkelhoff AJ, Laine ML, Peña AS.
    Genetic and microbial aspects of destructive periodontal disease.

    In: Tuncer O, Mutlu S, Scully C. Periodontal Tissue Destruction and Remodelling-Quintessence 2003. p. 1-10.
  5. Debets-Ossenkopp YJ, Reyes G, Mulder J, Aan De Stegge BM, Peters JT, Savelkoul PH, Tanca J, Pena AS, Vandenbroucke-Grauls CM.
    Characteristics of clinical Helicobacter pylori strains from Ecuador.
    J Antimicrob Chemother 2003;51:141-5.
  6. Bouma G and Strober W.
    The Immunological and genetic basis of inflammatory Bowel Disease.
    Nat Rev Immunol 2003;3(7):521-33.
  7. Schrijver HM., van As J., Crusius JBA, Dijkstra CD and Uitdehaag BMJ.
    IL1 gene polymorphisms: relevance of disease severity associated alleles with IL1-ß and IL-1ra production in multiple sclerosis.
    Mediators of Inflammation, 12 (2), April 2003, pag. 89-94.
  8. Van Bodegraven AA, Pena AS.
    Treatment of Extraintestinal Manifestations in Inflammatory Bowel Disease.

    Curr Treat Options Gastroenterol 2003;6:201-12.
  9. Gasche C, Alizadeh BZ, Peña AS.
    Genotype-phenotype correlations: how many disorders constitute inflammatory bowel disease?

    Review in depth. Europ J Gastroenterol & Hepatol juni 2003;15:1-8.
  10. van Veen T, Crusius JBA, van Winsen L, Xia B, Barkhof F, Peña AS, Polman CH, Uitdehaag BMJ.
    CTLA-4 and CD28 gene polymorphisms in susceptibility, clinical course and progression of multiple sclerosis.
    J Neuroimmunol 2003; 140 (1-2): 188-193.
  11. Peñate M, Cruz-Santamaría M, Mendoza JL, Peña AS, Díaz-Rubio M, García-Paredes J.
    Optimización en el tratamiento de formas complicadas de la enfermedad inflamatoria intestinal. Enfermedad de Crohn fistulizante.
    An Med Interna (Madrid) 2003; 20: 37-45.
  12. Mendoza JL, García-Paredes J, Peña AS, Cruz-Santamaría DM, Iglesias C, Díaz-Rubio M.
    A continuous spectrum of neutrophilic dermatoses in Crohn's disease.

    Rev Esp Enf Digest 2003;95:233-236

    Mendoza JL, García-Paredes J, Peña AS, Cruz-Santamaría DM, Iglesias C, Díaz-Rubio M.
    El espectro de las dermatitis neutrofílicas en la enfermedad de Crohn.
    Rev Esp Enf Digest 2003;95:229-232.
  13. Murillo LS, Land JA, Pleijster J, Bruggeman CA, Peña AS, Morré SA.
    Interleukin-1B (IL-1B) and interleukin-1 receptor antagonist (IL-1RN) gene polymorphisms are not associated with tubal pathology and Chlamydia trachomatis-related tubal factor subfertility.
    Hum Reprod 18(11): 2309-14.
  14. Murillo LS, Morré SA, Peña AS.
    Toll-like receptors and NOD/CARD proteins: pattern recognition receptors are key elements in the regulation of the immune response.
    Drugs of Today 2003, 39 (6): 415-438.
  15. Murillo LS, Morré SA, Peña AS.

    Role of the CARD15 gene in the pathogenesis of Crohn disease: phenotypic classification and prognostic implications.
    Scandinavian Journal of Gastroenterology 2003, 38 (11): 1107-14.

  16. zur Hausen A, Crusius JBA, Murillo LS, Morré SA, Alizadeh BZ, Meijer CJML, van den Brule AJC, Peña AS.
    IL-1B promoter polymorphism and Epstein-Barr virus in Dutch patients with gastric carcinoma.
    International Journal of Cancer 2003, 10; 107 (5): 866-7
  17. Garcia-Gonzalez, M. A., A. Lanas, Savelkoul PH, Santolaria S, Benito R, Crusius JB, Pena AS
    Association of interleukin 1 gene family polymorphisms with duodenal ulcer disease.
    Clin Exp Immunol 134(3): 525-31.
  18. Bayley JP, Baggen JM, Van de Pouw-Kraan T, Crusius JBA, Huizinga TWJ, Verweij CL.
    Association between polymorphisms in the human chemokine receptor genes CCR2 and CX3CR1 and rheumatoid arthritis.
    Tissue Antigens 2003;62(2):170-174.
  19. Hooper-van Veen T, Schrijver HM, Zwiers A, Crusius JBA, Knol DL, Kalkers NF, Laine ML, Barkhof F, Peña AS, Polman CH, Uitdehaag BMJ.
    The interleukin-1 gene family in multiple sclerosis susceptibility and disease course.
    Multiple Sclerosis 9: 535-539.
  20. van Veen T, Crusius JBA,  van Winsen L, Kalkers NF, Barkhof F, Peña AS, Polman CH, Uitdehaag BMJ.
    alphaB-crystallin genotype has impact on the multiple sclerosis phenotype.
    Neurology 61:1245-1249.
     
  21. Peña AS.
    Genetics of Inflammatory Bowel Disease- Past, Present and Future.
    Digestive Diseases 2003, 21:85-90.
  22. Karimi O, Peña AS.
    Probiotics: Isolated bacteria strain or mixtures of different strains? Two different approaches in the use of probiotics as therapeutics.
    Drugs of Today 2003, vol. 39 (8): 565-597
  23. Peña AS (Editorial)

    The value of serological and genetic markers in inflammatory bowel disease; Strength and weakness of the studies

    Rev Esp Enf Dig (Madrid) 2003;95 (11); 752-754.
  24. Peña AS. (Editorial)

    Change and progress in inflammatory bowel disease.
    Rev Esp Enf Dig (Madrid) 2003;95; N.° Extraordinario, pp. 65-67

  25. B. de Vries, R. van Beem, MAJM Jacobs, BMJ Uitdehaag, AS Peña.
    The concurrence of inflammatory bowel disease and multiple sclerosis
    Rev Esp Enf Dig (Madrid) 2003;95; N.° Extraordinario, pp. 120-125
  26. Seegers D, Borm ME, van Belzen MJ, Mulder CJJ, Bailing J, Crusius JBA, Meijer JWR, Wijmenga C, Peña AS, Bouma G.
    IL12B and IRF1 gene polymorphisms and susceptibility to celiac disease.
    Eur J Immunogenet 2003;30(6):421-425.
  27. Nemetz A,, Molnár T, ZágoniT, Kovács A, Tulassay Z, Nagy F, Peña AS.
    Phenotypes defined by the “Vienna Classification” in 100 Hungarian patients with Crohn’s disease
    Rev Esp Enferm Dig (Madrid)2003;Vol. 95. N.° 8, pp. 533-538     Spanish: Rev Esp Enferm Dig (Madrid)2003;Vol. 95. N.° 8, pp. 527-532
    English version   Spanish version  
  28. Gonzalez, C. A., S. Pena, Capella G.
    Clinical usefulness of virulence factors of Helicobacter pylori as predictors of the outcomes of infection. What is the evidence?
    Scand J Gastroenterol 38(9): 905-15.
     
  29. Mendoza JL, Murillo LS, Fernandez L, Pena AS, Lana R, Urcelay E, Cruz-Santamaria DM, de la Concha EG, Diaz-Rubio M, Garcia-Paredes J.
    Prevalence of mutations of the NOD2/CARD15 gene and relation to phenotype in Spanish patients with Crohn disease.
    Scand J Gastroenterol. 2003 Dec;38(12):1235-40.
  30. Karimi O, Peña AS
    Clinical Aspects of Probiotics: News on the horizon.
    In: "Inside Story: diet, intestinal flora and health". Publisher: Yakult Europe B.V. 2003. pp: 35-48